Antacids - chemistry in action

Since becoming pregnant, I’ve become acquainted with an uncomfortable stomach reality – heartburn. Or, more properly termed, pyrosis. If you’ve never had heartburn before, let me introduce you to the phenomenon. Your stomach is a very acidic environment – it has to be, to digest everything that you eat. The acid produced by your stomach is supposed to be kept in your stomach and out of your esophagus (the tube connecting your mouth to your digestive tract) through the action of the esophageal sphincter. It’s supposed to be a one-way valve that lets food and liquid from the esophagus into the stomach, but not the other way around. However, sometimes that sphincter doesn’t work very well, and stomach juices push up out of your stomach and into your esophagus. And as these juices are strongly acidic, they can burn whatever they touch; in this case, that would be the lining of your esophagus. This doesn’t really have anything to do with your heart, making heartburn rather poorly named. But since the burning sensation occurs right behind your breastbone, and in severe cases, radiate through the rest of your chest, I guess it makes sense for it to have gotten that name somewhere in the past.

Okay, so that’s heartburn – a burning sensation occurring in your esophagus. Fortunately for mild cases, there is a very simple remedy. Antacids. How do antacids work? It’s actually very simple chemistry in action. To stop heartburn, you want to stop the ability of the rising stomach acid to burn your esophagus. In other words, you want to neutralize the stomach acid. The opposite of an acid is a base. If you combine an acid and a base, they cancel each other out , resulting in something either neutral or closer to neutral than you started with (depending, of course, on the strength of each one). So, very simply, antacids contain some sort of base to help neutralize the stomach acid they encounter.

There are multiple kinds of antacids, each using a different chemical formulation to help neutralize stomach acid. Some, like Tums, use calcium carbonate. Others, like Alka-Seltzer, use sodium bicarbonate instead. There are also magnesium salt-based antacids, like Maalox and Mylanta. Each formula works very effectively, but there are limitations to them. People with hypertension have to be careful not to ingest too much sodium, so sodium bicarbonate antacids may not be recommended. And excess calcium or magnesium can cause kidney stones, so you don’t want to take too much of the other ones, either. All in all, antacids are like any over-the-counter medicine, I guess – you still have to be smart with what you take.

Incidentally, pregnant women frequently experience heartburn because there is less and less room in the abdomen as the baby grows. This puts pressure on the bottom of the stomach, often pushing the stomach juices up into the esophagus. But it’s not really that big a deal, at least for me. A few Tums usually clears things right up!

Yay for chemistry in action!